/* ONCO ATLAS v4 design layer: orange brand accents, charts, knowledge hub and AI assistant. */
:root{--brand:#c2410c;--brand-strong:#9a3412;--brand-bright:#f97316;--brand-soft:#fff1e6;--brand-tint:#ffedd5}
.rail{background:linear-gradient(180deg,#26170e 0%,#1a0f08 100%)}
.nav-button.active{background:linear-gradient(90deg,rgba(249,115,22,.22),rgba(249,115,22,.06));color:#fed7aa}
.nav-button.active:before{background:var(--brand-bright)}
.brand img{filter:drop-shadow(0 4px 10px rgba(249,115,22,.35))}
.page-heading .eyebrow{color:var(--brand)}
.btn.primary{background:linear-gradient(180deg,#d9530f,#c2410c);border-color:#b23c0b;box-shadow:0 1px 0 rgba(255,255,255,.18) inset,0 2px 8px rgba(194,65,12,.22)}
.btn.primary:hover{background:linear-gradient(180deg,#c2410c,#9a3412)}
.btn:hover{border-color:#f0b48c;background:#fff7f0}
.welcome{background:radial-gradient(circle at 85% 30%,rgba(251,146,60,.28),transparent 45%),linear-gradient(135deg,#fff3e8,#fde7d4);border-color:#f6d3b7}
.stat{transition:border-color .15s,box-shadow .15s}
.stat:hover{border-color:#f3c39f;box-shadow:0 6px 24px rgba(194,65,12,.08)}
.stat-label svg{color:var(--brand-bright)}
.panel{box-shadow:0 1px 2px rgba(43,29,20,.03)}
.memory-pill .dot,.dot{background:var(--brand-bright)}
.research-note{background:#fff5ec;border-color:#f6dcc6;color:#7a4a2c}
.research-note strong{color:#7c2d12}
.section-title{font-size:12px;font-weight:650;margin:4px 0 10px;color:var(--ink)}
.consent-banner{border:1px solid #f6cfae;background:linear-gradient(90deg,#fff4ea,#fffaf6);border-radius:10px;padding:13px 16px;margin-bottom:18px}
.consent-banner .checkline{font-size:11px}
.consent-banner strong{color:var(--brand-strong)}
.gene-card{border:1px solid var(--line);border-radius:10px;padding:16px;background:#fffdfb;margin-bottom:16px}
.gene-card h3{font-size:14px}
.gene-summary{font-size:12px;line-height:1.75;color:#4a3a2f;margin:10px 0}
.variant-grid{grid-template-columns:repeat(5,minmax(0,1fr))}
.annot-cell{display:flex;flex-direction:column;gap:5px;min-width:230px;font-size:11px}
.annot-cell strong{font-size:12px}
.annot-detail{margin-top:18px;padding-top:14px;border-top:1px solid var(--line)}
.annot-detail h3{font-size:14px;margin-bottom:4px}
.landscape{display:grid;grid-template-columns:minmax(0,auto) minmax(0,1fr);gap:28px;align-items:start}
.viz-wrap{min-width:0}
.viz-scroll{overflow-x:auto}
svg.viz{display:block;max-width:100%;height:auto;font-family:Instrument,Inter,system-ui,sans-serif;overflow:visible}
.viz-axis{font-size:10px;fill:#75604f}
.viz-label{font-size:11px;fill:#2b1d14;font-weight:600}
.viz-value{font-size:10px;fill:#75604f}
.viz-cell-text{font-size:10px;font-weight:650;pointer-events:none}
.viz-cell,.viz-dot,.viz-bar{outline:none}
.viz-cell.clickable,.viz-dot.clickable{cursor:pointer}
.viz-cell:hover rect,.viz-cell:focus-visible rect{stroke:#2b1d14;stroke-width:2}
.viz-dot:hover circle+circle,.viz-dot:focus-visible circle+circle{r:6.5;stroke:#2b1d14}
.viz-bar:hover path,.viz-bar:hover rect+rect,.viz-bar:focus-visible path{filter:brightness(.9)}
.viz-legend{display:flex;align-items:center;gap:10px;flex-wrap:wrap;font-size:10px;color:var(--muted);margin-top:10px}
.viz-ramp{display:inline-flex;border-radius:4px;overflow:hidden}
.viz-ramp i{width:14px;height:10px;display:inline-block}
.viz-key{display:inline-flex;align-items:center;gap:5px}
.viz-key i{width:12px;height:12px;border-radius:3px;display:inline-block}
.viz-key i.viz-none{border:1px dashed #d9c3b0;background:#fff}
.viz-tip{position:fixed;z-index:200;background:#2b1a10;color:#fff3e8;border-radius:8px;padding:8px 11px;font-size:11px;line-height:1.55;box-shadow:0 8px 28px rgba(43,26,16,.28);pointer-events:none;max-width:280px}
.viz-tip strong{display:block;color:#fdba74;font-size:12px}
.hbars{display:flex;flex-direction:column;gap:5px}
.hbar{display:grid;grid-template-columns:minmax(90px,38%) minmax(0,1fr) 54px;gap:10px;align-items:center;font-size:11px;padding:2px 4px;border-radius:5px;outline:none}
.hbar:hover,.hbar:focus-visible{background:#fff4ea}
.hbar-label{font-weight:600;overflow:hidden;text-overflow:ellipsis;white-space:nowrap;text-align:right;color:var(--ink)}
.hbar-track{height:14px;display:block}
.hbar-track i{display:block;height:100%;border-radius:0 4px 4px 0}
.hbar-value{color:var(--muted);font-variant-numeric:tabular-nums}
.checkline.inline{display:inline-flex;margin-right:14px}
.ai-preview{min-height:220px;font:11.5px/1.6 Consolas,monospace;background:#fffaf6}
.ai-response{border:1px solid var(--line);border-radius:10px;padding:16px;margin-bottom:14px;background:#fffdfb}
.ai-response h3{margin:10px 0 8px}
.ai-text{white-space:pre-wrap;overflow-wrap:anywhere;font-size:12.5px;line-height:1.75;color:#3a2a1f;margin-bottom:12px}
.hub-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px}
@media(max-width:1200px){.landscape{grid-template-columns:minmax(0,1fr)}.variant-grid{grid-template-columns:repeat(3,minmax(0,1fr))}}
@media(max-width:760px){.variant-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.hub-grid{grid-template-columns:1fr}}
@media print{.viz-tip,.consent-banner{display:none!important}}
dialog{max-width:880px}